2.2 SQUARE inside PROTEIN p0 inside PROTEIN p1 inside PROTEIN p2 inside PROTEIN p3 inside PROTEIN p4 inside SIMPLE_MOLECULE Biotinyl_minus_5_space__minus_AMP inside SIMPLE_MOLECULE _space_8_minus_Amino_minus_7_minus_oxononanoate inside SIMPLE_MOLECULE Biotin inside SIMPLE_MOLECULE _space_7_space_8_minus_Diaminononanoate inside SIMPLE_MOLECULE _space_6_minus_Carboxyhexanoyl_minus_CoA inside SIMPLE_MOLECULE Holo_minus__space_carboxylase_space_ inside SIMPLE_MOLECULE Dethiobiotin STATE_TRANSITION Dethiobiotin Biotin c6 c2 STATE_TRANSITION _space_6_minus_Carboxyhexanoyl_minus_CoA _space_8_minus_Amino_minus_7_minus_oxononanoate c4 c1 STATE_TRANSITION Biotinyl_minus_5_space__minus_AMP Holo_minus__space_carboxylase_space_ c0 c5 STATE_TRANSITION Biotin Biotinyl_minus_5_space__minus_AMP c2 c0 STATE_TRANSITION _space_7_space_8_minus_Diaminononanoate Dethiobiotin c3 c6 STATE_TRANSITION _space_8_minus_Amino_minus_7_minus_oxononanoate _space_7_space_8_minus_Diaminononanoate c1 c3