2.2 SQUARE inside PROTEIN p0 inside PROTEIN p1 inside SIMPLE_MOLECULE Tetrahydrofolate inside SIMPLE_MOLECULE Dihydrofolate inside SIMPLE_MOLECULE _space_5_space_10_minus_Methylenetetrahydrofolate STATE_TRANSITION _space_5_space_10_minus_Methylenetetrahydrofolate Dihydrofolate c2 c1 STATE_TRANSITION _space_5_space_10_minus_Methylenetetrahydrofolate Tetrahydrofolate c2 c0