2.2 SQUARE inside PROTEIN p0 inside PROTEIN p1 inside PROTEIN p2 inside PROTEIN p3 inside PROTEIN p4 inside SIMPLE_MOLECULE _space_6_minus_Pyruvoyltetrahydropterin inside SIMPLE_MOLECULE Folic_space_acid inside SIMPLE_MOLECULE _space_2_space_5_minus_Diamino_minus_6_minus__space_5_space__minus_triphosphoryl_minus_3_space__space_4_space__minus_trihydroxy_minus_2_space__minus_oxopentyl_space__minus_amino_minus_4_minus_oxopyrimidine inside SIMPLE_MOLECULE Tetrahydrofolyl_minus__space_Glu_space__space_n_space_ inside SIMPLE_MOLECULE Dihydrofolate inside SIMPLE_MOLECULE GTP inside SIMPLE_MOLECULE Tetrahydrofolyl_minus__space_Glu_space__space_2_space_ inside SIMPLE_MOLECULE Formamidopyrimidine_space_nucleoside_space_triphosphate inside SIMPLE_MOLECULE Tetrahydrofolate inside SIMPLE_MOLECULE _space_2_space_5_minus_Diaminopyrimidine_space_nucleoside_space_triphosphate inside SIMPLE_MOLECULE _space_2_minus_Amino_minus_4_minus_hydroxy_minus_6_minus__space_erythro_minus_1_space_2_space_3_minus_trihydroxypropyl_space_dihydropteridine_space_triphosphate inside SIMPLE_MOLECULE Dihydropteroate STATE_TRANSITION Tetrahydrofolate Dihydrofolate c8 c4 STATE_TRANSITION Dihydropteroate Dihydrofolate c11 c4 STATE_TRANSITION _space_2_minus_Amino_minus_4_minus_hydroxy_minus_6_minus__space_erythro_minus_1_space_2_space_3_minus_trihydroxypropyl_space_dihydropteridine_space_triphosphate _space_6_minus_Pyruvoyltetrahydropterin c10 c0 STATE_TRANSITION Tetrahydrofolyl_minus__space_Glu_space__space_n_space_ Tetrahydrofolyl_minus__space_Glu_space__space_n_space_ c3 c3 STATE_TRANSITION _space_2_space_5_minus_Diamino_minus_6_minus__space_5_space__minus_triphosphoryl_minus_3_space__space_4_space__minus_trihydroxy_minus_2_space__minus_oxopentyl_space__minus_amino_minus_4_minus_oxopyrimidine _space_2_minus_Amino_minus_4_minus_hydroxy_minus_6_minus__space_erythro_minus_1_space_2_space_3_minus_trihydroxypropyl_space_dihydropteridine_space_triphosphate c2 c10 STATE_TRANSITION Formamidopyrimidine_space_nucleoside_space_triphosphate _space_2_space_5_minus_Diaminopyrimidine_space_nucleoside_space_triphosphate c7 c9 STATE_TRANSITION _space_2_space_5_minus_Diaminopyrimidine_space_nucleoside_space_triphosphate _space_2_space_5_minus_Diamino_minus_6_minus__space_5_space__minus_triphosphoryl_minus_3_space__space_4_space__minus_trihydroxy_minus_2_space__minus_oxopentyl_space__minus_amino_minus_4_minus_oxopyrimidine c9 c2 STATE_TRANSITION Tetrahydrofolate Tetrahydrofolyl_minus__space_Glu_space__space_2_space_ c8 c6 STATE_TRANSITION Tetrahydrofolate Folic_space_acid c8 c1 STATE_TRANSITION GTP Formamidopyrimidine_space_nucleoside_space_triphosphate c5 c7 STATE_TRANSITION Folic_space_acid Dihydrofolate c1 c4