<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level2" version="1" level="2"
      xmlns:celldesigner="http://www.sbml.org/2001/ns/celldesigner">
	<model id="buc00020" name="buc00020">
		<annotation>
			<celldesigner:modelVersion>2.2</celldesigner:modelVersion>
			<celldesigner:modelDisplay sizeX="936" sizeY="715"/>
			<celldesigner:listOfCompartmentAliases>
				<celldesigner:compartmentAlias id="ca1" compartment="uVol">
					<celldesigner:class>SQUARE</celldesigner:class>
					<celldesigner:bounds x="10.0" y="10.0" w="916" h="695" />
				</celldesigner:compartmentAlias>
			</celldesigner:listOfCompartmentAliases>
			<celldesigner:listOfSpeciesAliases>
				<celldesigner:speciesAlias id="e0" species="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_" compartmentAlias="ca1">
					<celldesigner:bounds x="528" y="509" w="350" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="e1" species="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_" compartmentAlias="ca1">
					<celldesigner:bounds x="663" y="509" w="350" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="e2" species="dihydrolipoyl_space_dehydrogenanse" compartmentAlias="ca1">
					<celldesigner:bounds x="470" y="548" w="224" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="e3" species="dihydrolipoyllysine_minus_residue_space_succinyltransferase" compartmentAlias="ca1">
					<celldesigner:bounds x="405" y="509" w="329" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c0" species="_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP" compartmentAlias="ca1">
					<celldesigner:bounds x="617" y="517" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c1" species="_space_2_minus_Oxoglutarate" compartmentAlias="ca1">
					<celldesigner:bounds x="747" y="517" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c2" species="S_minus_Succinyldihydrolipoamide" compartmentAlias="ca1">
					<celldesigner:bounds x="487" y="518" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c3" species="Lipoamide" compartmentAlias="ca1">
					<celldesigner:bounds x="548" y="557" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c4" species="Succinyl_minus_CoA" compartmentAlias="ca1">
					<celldesigner:bounds x="359" y="518" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c5" species="Thiamin_space_diphosphate" compartmentAlias="ca1">
					<celldesigner:bounds x="616" y="478" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c6" species="CO2" compartmentAlias="ca1">
					<celldesigner:bounds x="645" y="490" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c7" species="Dihydrolipoamide" compartmentAlias="ca1">
					<celldesigner:bounds x="433" y="557" w="54" h="18"/>
				</celldesigner:speciesAlias>
			</celldesigner:listOfSpeciesAliases>
			<celldesigner:listOfProteins>
				<celldesigner:protein id="p0" type="GENERIC" name="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_">
				</celldesigner:protein>
				<celldesigner:protein id="p1" type="GENERIC" name="dihydrolipoyl_space_dehydrogenanse">
				</celldesigner:protein>
				<celldesigner:protein id="p2" type="GENERIC" name="dihydrolipoyllysine_minus_residue_space_succinyltransferase">
				</celldesigner:protein>
			</celldesigner:listOfProteins>
		</annotation>
		<listOfCompartments>
			<compartment id="default" name="default" />
			<compartment id="uVol" name="uVol" outside="default" />
		</listOfCompartments>
		<listOfSpecies>
			<species id="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_" name="oxoglutarate dehydrogenase (succinyl-transferring)" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p0</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R03316"/>
						<celldesigner:catalyzed reaction="R00621"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="dihydrolipoyl_space_dehydrogenanse" name="dihydrolipoyl dehydrogenanse" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p1</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R01698"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="dihydrolipoyllysine_minus_residue_space_succinyltransferase" name="dihydrolipoyllysine-residue succinyltransferase" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p2</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R02570"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP" name="3-Carboxy-1-hydroxypropyl-ThPP" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="_space_2_minus_Oxoglutarate" name="2-Oxoglutarate" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>_space_2_minus_Oxoglutarate</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="S_minus_Succinyldihydrolipoamide" name="S-Succinyldihydrolipoamide" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>S_minus_Succinyldihydrolipoamide</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="Lipoamide" name="Lipoamide" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>Lipoamide</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="Succinyl_minus_CoA" name="Succinyl-CoA" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>Succinyl_minus_CoA</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="Thiamin_space_diphosphate" name="Thiamin diphosphate" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>Thiamin_space_diphosphate</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="CO2" name="CO2" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>CO2</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="Dihydrolipoamide" name="Dihydrolipoamide" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>Dihydrolipoamide</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
		</listOfSpecies>
		<listOfReactions>
			<reaction id="R02570" name="R02570" reversible="true">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>S_minus_Succinyldihydrolipoamide</celldesigner:baseReactants>
					<celldesigner:baseProducts>Succinyl_minus_CoA</celldesigner:baseProducts>
					<celldesigner:listOfProductLinks>
						<celldesigner:productLink product="Dihydrolipoamide" alias="c7"/>
					</celldesigner:listOfProductLinks>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="dihydrolipoyllysine_minus_residue_space_succinyltransferase" aliases="e3"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="S_minus_Succinyldihydrolipoamide">
						<annotation>
							<celldesigner:alias>c2</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="Succinyl_minus_CoA">
						<annotation>
							<celldesigner:alias>c4</celldesigner:alias>
						</annotation>
					</speciesReference>
					<speciesReference species="Dihydrolipoamide">
						<annotation>
							<celldesigner:alias>c7</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="dihydrolipoyllysine_minus_residue_space_succinyltransferase"/>
				</listOfModifiers>
			</reaction>
			<reaction id="R03316" name="R03316" reversible="true">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP</celldesigner:baseReactants>
					<celldesigner:baseProducts>S_minus_Succinyldihydrolipoamide</celldesigner:baseProducts>
					<celldesigner:listOfReactantLinks>
						<celldesigner:reactantLink reactant="Lipoamide" alias="c3"/>
					</celldesigner:listOfReactantLinks>
					<celldesigner:listOfProductLinks>
						<celldesigner:productLink product="Thiamin_space_diphosphate" alias="c5"/>
					</celldesigner:listOfProductLinks>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_" aliases="e0"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP">
						<annotation>
							<celldesigner:alias>c0</celldesigner:alias>
						</annotation>
					</speciesReference>
					<speciesReference species="Lipoamide">
						<annotation>
							<celldesigner:alias>c3</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="S_minus_Succinyldihydrolipoamide">
						<annotation>
							<celldesigner:alias>c2</celldesigner:alias>
						</annotation>
					</speciesReference>
					<speciesReference species="Thiamin_space_diphosphate">
						<annotation>
							<celldesigner:alias>c5</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_"/>
				</listOfModifiers>
			</reaction>
			<reaction id="R00621" name="R00621" reversible="true">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>_space_2_minus_Oxoglutarate</celldesigner:baseReactants>
					<celldesigner:baseProducts>_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP</celldesigner:baseProducts>
					<celldesigner:listOfReactantLinks>
						<celldesigner:reactantLink reactant="Thiamin_space_diphosphate" alias="c5"/>
					</celldesigner:listOfReactantLinks>
					<celldesigner:listOfProductLinks>
						<celldesigner:productLink product="CO2" alias="c6"/>
					</celldesigner:listOfProductLinks>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_" aliases="e1"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="_space_2_minus_Oxoglutarate">
						<annotation>
							<celldesigner:alias>c1</celldesigner:alias>
						</annotation>
					</speciesReference>
					<speciesReference species="Thiamin_space_diphosphate">
						<annotation>
							<celldesigner:alias>c5</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="_space_3_minus_Carboxy_minus_1_minus_hydroxypropyl_minus_ThPP">
						<annotation>
							<celldesigner:alias>c0</celldesigner:alias>
						</annotation>
					</speciesReference>
					<speciesReference species="CO2">
						<annotation>
							<celldesigner:alias>c6</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="oxoglutarate_space_dehydrogenase_space__space_succinyl_minus_transferring_space_"/>
				</listOfModifiers>
			</reaction>
			<reaction id="R01698" name="R01698" reversible="true">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>Dihydrolipoamide</celldesigner:baseReactants>
					<celldesigner:baseProducts>Lipoamide</celldesigner:baseProducts>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="dihydrolipoyl_space_dehydrogenanse" aliases="e2"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="Dihydrolipoamide">
						<annotation>
							<celldesigner:alias>c7</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="Lipoamide">
						<annotation>
							<celldesigner:alias>c3</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="dihydrolipoyl_space_dehydrogenanse"/>
				</listOfModifiers>
			</reaction>
		</listOfReactions>
	</model>
</sbml>
