<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level2" version="1" level="2"
      xmlns:celldesigner="http://www.sbml.org/2001/ns/celldesigner">
	<model id="hsa00300" name="hsa00300">
		<annotation>
			<celldesigner:modelVersion>2.2</celldesigner:modelVersion>
			<celldesigner:modelDisplay sizeX="980" sizeY="744"/>
			<celldesigner:listOfCompartmentAliases>
				<celldesigner:compartmentAlias id="ca1" compartment="uVol">
					<celldesigner:class>SQUARE</celldesigner:class>
					<celldesigner:bounds x="10.0" y="10.0" w="960" h="724" />
				</celldesigner:compartmentAlias>
			</celldesigner:listOfCompartmentAliases>
			<celldesigner:listOfSpeciesAliases>
				<celldesigner:speciesAlias id="e0" species="_space_2_minus_aminoadipate_space_transaminase" compartmentAlias="ca1">
					<celldesigner:bounds x="384" y="536" w="216" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="e1" species="saccharopine_space_dehydrogenase_space__space_NAD_plus__space__space_L_minus_lysine_minus_forming_space_" compartmentAlias="ca1">
					<celldesigner:bounds x="678" y="427" w="357" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="e2" species="E2_space_3_space_1_space__minus_" compartmentAlias="ca1">
					<celldesigner:bounds x="583" y="124" w="56" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="e3" species="lysine_minus_tRNA_space_ligase" compartmentAlias="ca1">
					<celldesigner:bounds x="762" y="394" w="144" h="15.0"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c0" species="N6_minus__space_L_minus_1_space_3_minus_Dicarboxypropyl_space__minus_L_minus_lysine" compartmentAlias="ca1">
					<celldesigner:bounds x="658" y="446" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c1" species="L_minus_Lysine" compartmentAlias="ca1">
					<celldesigner:bounds x="743" y="446" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c2" species="L_minus_Lysyl_minus_tRNA" compartmentAlias="ca1">
					<celldesigner:bounds x="829" y="402" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c3" species="_space_2_space_3_space_4_space_5_minus_Tetrahydrodipicolinate" compartmentAlias="ca1">
					<celldesigner:bounds x="536" y="199" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c4" species="_space_2_minus_Oxoadipate" compartmentAlias="ca1">
					<celldesigner:bounds x="406" y="578" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c5" species="N_minus_Acetyl_minus_L_minus_2_minus_amino_minus_6_minus_oxopimelate" compartmentAlias="ca1">
					<celldesigner:bounds x="681" y="132" w="54" h="18"/>
				</celldesigner:speciesAlias>
				<celldesigner:speciesAlias id="c6" species="L_minus_2_minus_Aminoadipate" compartmentAlias="ca1">
					<celldesigner:bounds x="406" y="512" w="54" h="18"/>
				</celldesigner:speciesAlias>
			</celldesigner:listOfSpeciesAliases>
			<celldesigner:listOfProteins>
				<celldesigner:protein id="p0" type="GENERIC" name="_space_2_minus_aminoadipate_space_transaminase">
				</celldesigner:protein>
				<celldesigner:protein id="p1" type="GENERIC" name="saccharopine_space_dehydrogenase_space__space_NAD_plus__space__space_L_minus_lysine_minus_forming_space_">
				</celldesigner:protein>
				<celldesigner:protein id="p2" type="GENERIC" name="E2_space_3_space_1_space__minus_">
				</celldesigner:protein>
				<celldesigner:protein id="p3" type="GENERIC" name="lysine_minus_tRNA_space_ligase">
				</celldesigner:protein>
			</celldesigner:listOfProteins>
		</annotation>
		<listOfCompartments>
			<compartment id="default" name="default" />
			<compartment id="uVol" name="uVol" outside="default" />
		</listOfCompartments>
		<listOfSpecies>
			<species id="_space_2_minus_aminoadipate_space_transaminase" name="2-aminoadipate transaminase" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p0</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R01939"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="saccharopine_space_dehydrogenase_space__space_NAD_plus__space__space_L_minus_lysine_minus_forming_space_" name="saccharopine dehydrogenase (NAD+, L-lysine-forming)" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p1</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R00715"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="E2_space_3_space_1_space__minus_" name="2.3.1.-" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p2</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R04364"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="lysine_minus_tRNA_space_ligase" name="lysine-tRNA ligase" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>PROTEIN</celldesigner:class>
						<celldesigner:proteinReference>p3</celldesigner:proteinReference>
					</celldesigner:speciesIdentity>
					<celldesigner:listOfCatalyzedReactions>
						<celldesigner:catalyzed reaction="R03658"/>
					</celldesigner:listOfCatalyzedReactions>
				</annotation>
			</species>
			<species id="N6_minus__space_L_minus_1_space_3_minus_Dicarboxypropyl_space__minus_L_minus_lysine" name="N6-(L-1,3-Dicarboxypropyl)-L-lysine" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>N6_minus__space_L_minus_1_space_3_minus_Dicarboxypropyl_space__minus_L_minus_lysine</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="L_minus_Lysine" name="L-Lysine" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>L_minus_Lysine</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="L_minus_Lysyl_minus_tRNA" name="L-Lysyl-tRNA" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>RNA</celldesigner:class>
						<celldesigner:name>L_minus_Lysyl_minus_tRNA</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="_space_2_space_3_space_4_space_5_minus_Tetrahydrodipicolinate" name="2,3,4,5-Tetrahydrodipicolinate" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>_space_2_space_3_space_4_space_5_minus_Tetrahydrodipicolinate</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="_space_2_minus_Oxoadipate" name="2-Oxoadipate" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>_space_2_minus_Oxoadipate</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="N_minus_Acetyl_minus_L_minus_2_minus_amino_minus_6_minus_oxopimelate" name="N-Acetyl-L-2-amino-6-oxopimelate" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>N_minus_Acetyl_minus_L_minus_2_minus_amino_minus_6_minus_oxopimelate</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
			<species id="L_minus_2_minus_Aminoadipate" name="L-2-Aminoadipate" compartment="uVol" initialAmount="0.0">
				<annotation>
					<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
					<celldesigner:speciesIdentity>
						<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
						<celldesigner:name>L_minus_2_minus_Aminoadipate</celldesigner:name>
					</celldesigner:speciesIdentity>
				</annotation>
			</species>
		</listOfSpecies>
		<listOfReactions>
			<reaction id="R00715" name="R00715" reversible="true">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>N6_minus__space_L_minus_1_space_3_minus_Dicarboxypropyl_space__minus_L_minus_lysine</celldesigner:baseReactants>
					<celldesigner:baseProducts>L_minus_Lysine</celldesigner:baseProducts>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="saccharopine_space_dehydrogenase_space__space_NAD_plus__space__space_L_minus_lysine_minus_forming_space_" aliases="e1"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="N6_minus__space_L_minus_1_space_3_minus_Dicarboxypropyl_space__minus_L_minus_lysine">
						<annotation>
							<celldesigner:alias>c0</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="L_minus_Lysine">
						<annotation>
							<celldesigner:alias>c1</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="saccharopine_space_dehydrogenase_space__space_NAD_plus__space__space_L_minus_lysine_minus_forming_space_"/>
				</listOfModifiers>
			</reaction>
			<reaction id="R01939" name="R01939" reversible="true">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>L_minus_2_minus_Aminoadipate</celldesigner:baseReactants>
					<celldesigner:baseProducts>_space_2_minus_Oxoadipate</celldesigner:baseProducts>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="_space_2_minus_aminoadipate_space_transaminase" aliases="e0"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="L_minus_2_minus_Aminoadipate">
						<annotation>
							<celldesigner:alias>c6</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="_space_2_minus_Oxoadipate">
						<annotation>
							<celldesigner:alias>c4</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="_space_2_minus_aminoadipate_space_transaminase"/>
				</listOfModifiers>
			</reaction>
			<reaction id="R03658" name="R03658" reversible="false">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>L_minus_Lysine</celldesigner:baseReactants>
					<celldesigner:baseProducts>L_minus_Lysyl_minus_tRNA</celldesigner:baseProducts>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="lysine_minus_tRNA_space_ligase" aliases="e3"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="L_minus_Lysine">
						<annotation>
							<celldesigner:alias>c1</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="L_minus_Lysyl_minus_tRNA">
						<annotation>
							<celldesigner:alias>c2</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="lysine_minus_tRNA_space_ligase"/>
				</listOfModifiers>
			</reaction>
			<reaction id="R04364" name="R04364" reversible="false">
				<annotation>
					<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
					<celldesigner:baseReactants>_space_2_space_3_space_4_space_5_minus_Tetrahydrodipicolinate</celldesigner:baseReactants>
					<celldesigner:baseProducts>N_minus_Acetyl_minus_L_minus_2_minus_amino_minus_6_minus_oxopimelate</celldesigner:baseProducts>
					<celldesigner:listOfModification>
						<celldesigner:modification type="CATALYSIS" modifiers="E2_space_3_space_1_space__minus_" aliases="e2"/>
					</celldesigner:listOfModification>
				</annotation>
				<listOfReactants>
					<speciesReference species="_space_2_space_3_space_4_space_5_minus_Tetrahydrodipicolinate">
						<annotation>
							<celldesigner:alias>c3</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfReactants>
				<listOfProducts>
					<speciesReference species="N_minus_Acetyl_minus_L_minus_2_minus_amino_minus_6_minus_oxopimelate">
						<annotation>
							<celldesigner:alias>c5</celldesigner:alias>
						</annotation>
					</speciesReference>
				</listOfProducts>
				<listOfModifiers>
					<modifierSpeciesReference species="E2_space_3_space_1_space__minus_"/>
				</listOfModifiers>
			</reaction>
		</listOfReactions>
	</model>
</sbml>
