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October 2005 Selection
News Feature, Drug Discovery: Playing Dirty, Nature 13, Oct. 2005
A news feature article Drug discovery: Playing dirty by Simon Frantz focuses on complex relationship between genes and diseases. Some "dirty" drugs under development interacts with multiple kinases at the same time.
WTEC Report: Assessment of International Research and Development in Systems Biology
W-TEC report that represents US view on current state of systems biology and assessment of competitive strength of each coutry they have investigated is now on-line.

According to the web site, "The goal of this study is to gather information on the worldwide status and trends in systems biology: “Network Behavior in Biological Systems” and to disseminate it to government decision makers and the research community

The study panelists will gather information on systems biology abroad useful to the U.S. government in its own R&D programs, and will critically analyze and compare the research in the United States with that being pursued in Japan, Europe, or other major industrialized countries. This information will serve the following purposes:
(1) Identify good ideas overseas worth exploring in U.S. R&D programs, (2) Clarify research opportunities and needs for promoting progress in the field generally, (3)Identify opportunities for international collaboration, and (4) Evaluate the position of foreign research programs relative to those in the U.S."
Towards a proteome-scale map of the human protein-protein interaction network, Rual, JF., et al., Nature, 2005
Jean-Francois Rual, et al.,
Towards a proteome-scale map of the human protein-protein interaction network,
Nature, Advanced On-line Publication, doi: 10.1038/nature04209
A network-based analysis of systemic inflammation in humans, Calvano, et al., Nature, 13 Oct. 2005
Steve E. Calvano, et al.,
A network-based analysis of systemic inflammation in humans
Nature 437, 1032-1037 (13 October 2005) | doi: 10.1038/nature03985
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